Palmer, who concluded: “The results for these exercise programs are similar. The majority of patients in both groups showed improvements in: gait, tremor, grip strength and coordination, in activities requiring fine control of movement.

Probably the most promising and best studied candidate target for disease modification is exercise,5 primarily referred to in this article as (the volume and intensity of) aerobic exercise. Furthermore, preliminary neuroimaging evidence from the Park-in-Shape trial—where magnetic resonance imaging scans were performed before and after exercise—suggests that engaging in regular aerobic exercise can be associated with an improved preservation of the basal ganglia network and hence a slowing of the disease. Article published 2022.

Lisa Shulman M.D. and other researchers at the University of Maryland School of Medicine and the Baltimore VA Medical Center found that Parkinson’s patients who walked on a treadmill at a moderate speed for a long time (low-intensity exercise) had greater improvements in mobility and dexterity, compared to patients who walked for a shorter time, but at a greater speed and inclination (high intensity exercise). The researchers also noted improvements in mobility and strength. “These results show that exercise for people with Parkinson’s disease can make a difference in movement function. Exercise can actually delay disability and help maintain independence,” explains Lisa Shulman, M.D.

In a study of positive outcomes in Parkinson’s disease. More than three-quarters (82%) of people with Parkinson’s (PwPs) said that there are positive sides to having the condition, in a recent study co-authored by Dr Bastiaan Bloem. PwPs were asked the controversial question via social media and their responses have been recorded in ‘The silver linings of Parkinson’s’, published in research journal ‘npj Parkinson’s disease’.
Finding a new purpose in life, improved relationships – as well as healthier lifestyle choices, such as increased exercise and better work–life balance were among the ‘silver linings’ listed by the majority of the test group had a positive response.

Harvard Medical School. According to the March 2012 Harvard Health Letter, exercise may be one of the best – and least used – ways to fight Parkinson’s disease. Dr. Edward Wolpow, a neurologist at Mount Auburn Hospital in Cambridge, Mass., (a Harvard-affiliated institution) and a member of the editorial board of the Harvard Health Letter, urges his early-stage Parkinson’s patients to exercise to improve their strength, balance and resistance “because they will need it later

“Anouk Tosserams, MD et al 2021” The main findings are as follows: (1) compensation strategies for gait impairments are commonly used by persons with PD, but their awareness of the full spectrum of available strategies is limited; (2) the patient-rated efficacy of compensation strategies is high but varies depending on the context in which they are applied; and (3) compensation strategies are useful for all types of patients with PD, but the efficacy of the different strategies varies per person. of particular concern is that of all respondents, 22.8% had never tried any form of compensation strategies before, despite experiencing clear and sometimes disabling gait impairments.

Parkinson’s outcome project interim research report stated “the quality of life of a person with Parkinson’s is directly related to his or her mood”, in other words it is NOT Parkinson’s that will destroy our quality of life but rather our emotions to having Parkinson’s. Apathy, Fear, depression and fear. “Our goal as physicians is to not just help you function better, but to help you feel better. There is a difference between function and feeling, and we have found that how people with Parkinson’s feel—their mood and depression—is a critical factor with a tangible impact on overall health.” And “The symptoms patients report as having the most effect on their health status are “negative mood and depression”.

Toward a Neuroplasticity-principled Rehabilitation Model. The use of exercise as a physiologic tool to promote the body’s own endogenous brainrepair mechanisms is a virtually untapped resource for people with PD. Research in the area of exercise neurobiology has shown that exercise may interfere with a positive response to multiple mechanisms involved in cell death, stimulate the proliferation of new neurons,35,36 alter metabolic and immune system responses,  increase blood supply and protect against the “erosive neural events of aging, neurodegeneration, and brain injury.”

Il Dott. Zigmond et al., della University of Pittsburgh hanno scoperto che l’esercizio fisico riduce gli effetti negativi “indotti dalla neurotossina dopaminergica così come la perdita di neuroni dopaminergici”

Overall, these findings provide a confirmatory evidence of previous data showing that neuropsychiatric symptoms, especially depression, night-time sleep disorders, fatigue and somnolence, are the variables that most affect the HRQoL of patients with PD [24–26]. Thus, our data demonstrate that non-motor symptoms are negatively associated with patients’ health perception. The results of our data suggest that the presence of non-motor symptoms, such as fatigue, depression and sleep disruption, have a significant impact on psychological well-being in PD patients. Therefore, our findings confirm the previous evidence on the burden of non-motor symptoms as a key determinant of psychological well-being in PD. Alessandra Nicoletti et al 2017

Dr. Alberts et al., of the Cleveland Clinic, determined that Parkinson’s patients who cycled at a speed 30% faster than their voluntary speed (high-intensity exercise) showed improvements in motor function, coordination, as well as in manual dexterity. Furthermore, this progress persisted up to a few weeks after the end of the exercise program. Jay L. Alberts discovered almost by accident how good bicycling can be for him while riding a tandem bike through Iowa with a friend who has Parkinson’s. Something surprising happened: although the condition had already robbed her of her ability to write legibly, her friend was able to write her name clearly after her first day on the bike.

Beth Fisher and other researchers at the University of Southern California are convinced that exercise can help maintain brain connections, form new ones and repair damaged ones. Suggesting that, in certain situations, exercise-induced neuroplasticity in Parkinson’s patients could overcome the effects of neurodegeneration.

Hirsch (University of North Carolina) e Farley (University of Arizona) in un articolo pubblicato sull’European Journal of Physical Medicine del giugno 2009, si lamentano del fatto che “molti specialisti rimangono ignari” sulla letteratura scientifica che tratta della riparazione cerebrale indotta dall’esercizio.

A Model Community NeuroFitness Center of Excellence for Parkinson Exercise in Tucson, AZ. Sponsored by Parkinson Wellness Recovery, a 501(3)(C) nonprofit organization founded by Dr. Becky Farley. All PWR! Gym programs implement the research-based Exercise4BrainChange framework created by Dr. Farley to truly implement Exercise as Medicine for people with Parkinson disease. We are developing the

Foods largely comprise the Mediterranean diet, which has been associated with reduced PD incidence and later age of diagnosis [9]. Likewise, there is evidence that this diet decreases risk and progression of Alzheimer’s disease, a related neurodegenerative disorder. Of all the nutritional supplements studied, only coenzyme Q10 and fish oil were associated with statistically significant reduced rates of PD progression. Laurie K. Mischley et al

Dr. M.R. Salati of the Fidenza Hospital (Parma, Italy) indicates that “in Parkinson’s disease it is useful from the early stages to carry out physical exercises to improve coordination and muscle tone and prevent muscle shortening and alterations” in capsular ligamental articulation ”. The exercises should be performed daily once the patient has been adequately instructed during rehabilitation therapy.